Ah, if only it were that clear….
But don’t discount it yet. What we do know is that:
Rheumatoid arthritis (RA) and periodontitis are both chronic inflammatory diseases.
The vast majority of clinical and epidemiological studies indicate that patients with RA have an increased prevalence of periodontitis and tooth loss.
A US population-based study on the over 60s showed that people with four out of six criteria for RA had a fourfold increased risk of having periodontitis, after adjusting for age, sex, ethnicity and smoking.
Periodontitis might be an important modifiable risk factor for RA.
What we don’t yet know is the mechanism for the association. Is RA a causal factor for periodontitis for example through systemic bone loss, medications used to control inflammation or loss of manual dexterity leading to plaque accumulation? Is periodontitis a trigger for a breach in immune tolerance in RA patients, thereby initiating and/or sustaining the immune-mediated inflammatory joint injury in RA? Or could the relationship simply be a result of exposure to common genetic, environmental or behavioural factors?
The 2009 paper by dePablo, Chapple, Buckley & Dietrich, in the influential journal Nature Reviews Rheumatology on “Periodontitis in Systemic Rheumatic Diseases” reviews the science and proposes a number of biologically plausible causal and non-causal mechanisms which could account for the association. If you are interested to learn more, follow the link to the abstract here.
Further research is underway and the European Union have funded a large consortium of researchers in Rheumatology and Periodontology (including those from Birmingham UK above), whose aim is to help clarify some of the issues raised in the review paper concerning the relationship between periodontitis and RA.
Certainly RA patient groups would much rather control their RA symptoms by improving and maintaining their periodontal health, than taking many of the unpleasant drugs they currently have to take, with significant associated side effects.
Meanwhile, this simply adds to the growing number of reasons to take care of your gums.